EDUCATION:
The Ohio State University, Columbus, OH
PhD in Biophysics, December 2016
MS in Biophysics, June 2015
Cornell University
M.Eng in Chemical Engineering, February 2010
AB/BS in Biology and Chemical Engineering, May 2008
RESEARCH EXPERIENCE:
Postdoctoral Researcher, (January 2017 to Present), Department of Biomedical Informatics, The Ohio State University, Columbus, OH
Graduate Research Associate (June 2013 to December 2016), Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH
Research Assistant (November 2010 to June 2012), Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH
Undergraduate Research Assistant (August 2006 to May 2008), Cornell University, Ithaca, NY
Student Research Assistant (May 2006 to August 2006), The Ohio State University, Columbus, OH
INTERNSHIP EXPERIENCE:
Licensing Intern (January 2014 to June 2015), Technology Commercialization Office, The Ohio State University, Columbus, OH
Chemical Engineering Intern (May 2007 to August 2007), The Lubrizol Corporation, Wickliffe, OH
SKILLS:
Mathematical Modeling
Protein Purification
Molecular Biology
Fluorescence Spectroscopy
TEACHING/ADVISING EXPERIENCE:
Undergraduate Research Mentor (2013-Present), Physiology and Cell Biology, The Ohio State University,
Group Leader/Coordinator for Biophysics Seminar Discussion Group (2015), The Ohio State University,
Tutor for Physiology course, The Ohio State University
Volunteer Teaching/Science Demonstrations (2013 -2014), Hilltonia Middle School, Columbus, OH
PUBLICATIONS:
Siddiqui, J.K., Baskin, E., Liu, M., Cantemir-Stone, C.Z., Zhang, B., Bonneville, R., McElroy, J.P., Coombes, K.R. and Mathé, E.A., 2018. IntLIM: integration using linear models of metabolomics and gene expression data. BMC bioinformatics, 19(1), p.81.
Zhang, B., Hu, S., Baskin, E., Patt, A., Siddiqui, J.K. and Mathé, E.A., 2018. RaMP: A Comprehensive Relational Database of Metabolomics Pathways for Pathway Enrichment Analysis of Genes and Metabolites. Metabolites, 8(1), p.16.
Siddiqui, J. K., Tikunova, S. B., Walton, S. D., Liu, B., Meyer, M., de Tombe, P. P., Neilson, N., Kekenes-Huskey, P.M., Salhi, H.E., Janssen, P.M.L., Biesiadecki, B. J., & Davis, J.P. (2016). Myofilament calcium sensitivity: Consequences of the effective concentration of troponin I. Frontiers in Physiology, 7, 632.
Walton, S. D., Chakravarthy, H., Shettigar, V., O’Neil, A. J., Siddiqui, J. K., Jones, B. R., ... & Davis, J. P. (2017). Divergent Soybean Calmodulins Respond Similarly to Calcium Transients: Insight into Differential Target Regulation. Frontiers in plant science, 8.
Salhi, H. E., Hassel, N. C., Siddiqui, J. K., Brundage, E. A., Ziolo, M. T., Janssen, P. M., Davis, J.P., & Biesiadecki, B. J. (2016). Myofilament calcium sensitivity: mechanistic insight into TnI Ser-23/24 and Ser-150 phosphorylation integration. Frontiers in Physiology, 7.
Davis, J. P., Shettigar, V., Tikunova, S. B., Little, S. C., Liu, B., Siddiqui, J. K., Janssen, P.M.L., Ziolo, M.T., & Walton, S. D. (2016). Designing proteins to combat disease: Cardiac troponin C as an example. Archives of Biochemistry and Biophysics, 601, 4-10.
Asp, M. L., Sjaastad, F. V., Siddiqui, J. K., Davis, J. P., & Metzger, J. M. (2016). Effects of Modified Parvalbumin EF-Hand Motifs on Cardiac Myocyte Contractile Function. Biophysical Journal, 110(9), 2094-2105.
Liu, B., Tikunova, S. B., Kline, K. P., Siddiqui, J. K., & Davis, J. P. (2012). Disease-related cardiac troponins alter thin filament Ca 2+ association and dissociation rates. PloS One, 7(6), e38259.
Nayak, S., Siddiqui, J. K., & Varner, J. D. (2011). Modelling and analysis of an ensemble of eukaryotic translation initiation models. IET Systems Biology, 5(1), 2-14.
CONFERENCE PRESENTATIONS:
Siddiqui, J. K., Liu, B., Walton, S. D., Shettigar, V. K., O'Neil, A. J., Davis, G. A., ... & Davis, J. P. (2016). Modeling the Response of Cardiac Troponin C to Calcium on the Thin Filament: Effects of Disease-Related and Post-Translational Modifications. Poster session presented at the Biophysical Society Meeting. Los Angeles, CA. Biophysical Journal, 110(3), 123a.
Siddiqui, J. K., Liu, B., Walton, S. D., Shettigar, V. K., O’Neil, A. J., Davis, G. A., ... & Davis, J. P. (2015). Modeling the Response of Cardiac Troponin C to Calcium on the Thin Filament: Effects of Disease-Related and Post-Translational Modifications. Poster session presented at the Biophysical Society Meeting. Baltimore, MD. Biophysical Journal, 108(2), 596a-597a.
Siddiqui, J. K., Liu, B., and Davis, J.P. (2012). Kinetic Modeling of the Response of Cardiac Troponin C in Increasingly Complex Systems. Poster session presented at the Myofilament Meeting. Madison, WI.
REFERENCES:
Available Upon Request